Craig Venter
We report the design, synthesis and assembly of the 1.08-
Mbp Mycoplasma mycoides JCVI-syn1.0 genome starting
from digitized genome sequence information and its
transplantation into a Mycoplasma capricolum recipient
cell to create new Mycoplasma mycoides cells that are
controlled only by the synthetic chromosome. The only
DNA in the cells is the designed synthetic DNA sequence,
including “watermark” sequences and other designed
gene deletions and polymorphisms, and mutations
acquired during the building process. The new cells have
expected phenotypic properties and are capable of
continuous self-replication.
Mbp Mycoplasma mycoides JCVI-syn1.0 genome starting
from digitized genome sequence information and its
transplantation into a Mycoplasma capricolum recipient
cell to create new Mycoplasma mycoides cells that are
controlled only by the synthetic chromosome. The only
DNA in the cells is the designed synthetic DNA sequence,
including “watermark” sequences and other designed
gene deletions and polymorphisms, and mutations
acquired during the building process. The new cells have
expected phenotypic properties and are capable of
continuous self-replication.
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Si a alguien le interesa leer este artículo el pdf se encuentra en la wiki.
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